贵州省黔东南州凯里市剑辉化工制造有限公司

SR-121463A  185913-79-5

价格:8600元/公斤 含量:99% 包装:25公斤

CAS;185913-79-5

分子式:C17H22ClNO3

分子量:323.8228

化学名称 N-tert-Butyl-4-[539;-ethoxy-4-[2-(4-morpholinyl)ethoxy]-239;-oxospiro[cyclohexane-1,339;-indolin]-139;-ylsulfonyl]-3-methoxybenzamide fumarate

The reduction of diethyl 3-(methoxymethoxy)glutarate (I) with LiAlH4 in THF gives 3-(methoxymethoxy)pentane-1,5-diol (II), which is treated with Ts-OH and TEA in THF to yield the disulfonate (III). The condensation of (III) with 5-ethoxyindolin-2-one (IV) by means of tBu-OK in THF affords the spiro compound (V), which is deprotected with HCl in methanol to afford the spiranic alcohol (VI). The oxidation of (VI) with pyridinium chlorochromate (PCC) over Al2O3 provides the spiranic cyclohexanone (VII), which is treated with 2-chloroethanol (VIII) and Ms-OH in toluene to give the ketal (IX). The reaction of (IX) with zinc borohydride and trimethylsilyl chloride in ethyl ether/dichloromethane yields the 2-chloroethoxy derivative (X), which is condensed with 4-(N-tert-butylcarbamoyl)-2-methoxybenzenesulfonyl chloride (XI) by means of tBu-OK in THF to afford the adduct (XII). Finally, the target compound is obtained by condensation of (XII) with morpholine (XIII) by means of NaI in DMF, followed by treatment with fumaric acid.

Bromophenylethylketone 23022-83-5

Alpha 2114-00-3

UR 1431 Hydrochloride 49656-78-2

3-Chloropropiophenone 936-59-4

propiophenone 93-55-0

Chloroephedrine HCL 110925-64-9

chloroephedrine 27270-80-0

PHENYLPROPANOLAMINE 14838-15-4

甲鞍基笨柄酮 2538-50-3

Topiroxostat 577778-58-6

THC 1972-08-3

MDA 4764-17-4

MDMA 42542-10-9 

GHB 591-81-1

nimetazepam 2011-67-8

desomorphine 427-00-9 

triazolam 28911-01-5

Thionyl chloride 7719-09-7

EPHEDRINE 299-42-3

EINECS 269-531-5

aniracetam 72432-10-1

Chloroephedrine HCL 110925-64-9

hydrochloride 27270-80-0

chloroephedrine 25394-33-6

Loratadine 79794-75-5

Ephedrine hydrochloride 50-98-6

ENDO-NORBORNEO 134-71-4

4-hydroxyephedrine-hydrochloride 7437-54-9

Ephedrol 24221-86-1

Mapenterol hydrochloride 54238-51-6

L-PAC 1798-60-3

UNII-Y24T9BT2Q2 33817-09-3

6-MDMA 138808-79-4

methylamphetamine 64-11-9

methamphetamine-D5 60124-88-1

MDMA hydrochloride salt

Methamphetamine 4846-07-5

desoxyn 51-57-0 

(S)-METHYLENEDIOXYMETHAMPHETAMINE 66142-89-0

4-phenylbutan-2-amine 22374-89-6

3,4-Methylenedioxy Methamphetamine Hydrochloride 64057-70-1

rac Pholedrine 370-14-9 

methamphetamine 537-46-2